Did you know that a diagonal crease in the earlobe could be an early indicator of cardiovascular disease? A recent study from the American Journal of Medicine found that there was a high prevalence of this crease in individuals who suffer from coronary artery disease.
Frank’s Sign was named after American pulmonologist Sander T. Frank, who first observed the diagonal crease in multiple patients suffering from angina. The crease, or wrinkle, typically runs diagonally across the earlobe. Having Frank’s sign doesn’t necessarily mean that you will develop coronary artery disease; however, there is a strong association between the two.
Frank’s Sign is incredibly common, especially in older individuals. Steven Spielberg, George W. Bush, and Dick Van Dyke all have visible creases in their earlobes. Some research indicates that Frank’s Sign may also be associated with other forms of chronic disease, including cerebrovascular conditions and more; however, researchers need more time to study this phenomenon to fully understand what this sign could mean for our overall health.
How is Frank’s Sign Associated with Coronary Artery Disease?
Unfortunately, it remains unclear why ear creases are so heavily associated with coronary artery disease and heart attack. Some researchers postulate that both are caused by the same underlying bodily process. For example, when the heart’s vessels become damaged, the body also experiences a loss of elastin, which could cause earlobe creases. Another theory suggests that the crease itself isn’t a risk factor, rather a byproduct of other known cardiovascular risk factors, including age, diabetes, high blood pressure, and more.
Other Risk Factors for Heart Disease
Your doctor is unlikely to look first at your ear lobes when assessing your risk for coronary artery disease and heart attack. Far more proven risk factors for heart disease include:
- Age
- Gender
- Family History
- Smoking/Alcohol Abuse
- High Blood Pressure
- Diabetes
- High Cholesterol
- Obesity
- Stress
Other factors could play a role in determining your individual risk for heart disease. To better understand your risk, consult a TPMG primary care provider in Hampton Roads, or make an appointment with TPMG Heart and Vascular Center in Newport News, VA.
When to See a Doctor
If you notice an ear crease, and you have concerns about your risk for coronary artery disease and heart attack, talk to a TPMG primary care provider about how you can reduce your risk and find treatment for heart conditions. While many people with Frank’s Sign experience no heart issues, if you notice an ear crease in conjunction with symptoms of chest pain, neck or upper back pain, nausea, heartburn, indigestion, extreme fatigue, shortness of breath, dizziness, heart palpitations, or excessive swelling (edema) in your feet, ankles, legs, abdomen, or neck veins, make an appointment with TPMG Heart and Vascular Center in Newport News, VA.
For acute symptoms of severe pain or pressure in the center of the chest, pain that spreads from the chest to the arms, shoulder, neck, or chest discomfort accompanied by nausea, fainting, or sweating, seek emergency medical attention immediately.
Make an Appointment with Our Heart Specialists in Newport News, VA
If you or your primary care provider are concerned about your cardiovascular health, make an appointment with TPMG Heart and Vascular Center in Newport News, VA. We provide comprehensive cardiology services, offer our patients prompt scheduling, and provide your family physician with cardiac test results quickly. To make an appointment with our heart specialists in Newport News, VA, call (757) 875-5332.Â
The information shared is not intended to be medical advice, nor is it meant to replace a professional consultation with a healthcare provider. The opinions expressed do not necessarily reflect those of TPMG or its providers and physicians.







