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TPMG Conducts cSUI Clinical Research Study

Newport News, VA, December 15, 2020 – TPMG Clinical Research Division in Newport News is conducting a clinical research study for women who experience bladder leaks due to chronic cough induced stress urinary incontinence, or cSUI. The purpose of this study is to evaluate an investigational drug, MK-7264-042, to determine if it may be a safe and effective treatment for cSUI. Newport News Clinical Research Director, Linda Schneider, MD, MBA, FAAFP, is the lead investigator conducting this study.

Stress urinary incontinence (SUI) occurs when you leak urine unintentionally as a result of pressure, or stress, on your bladder. This stress happens during physical movements or activities, such as coughing, sneezing, running, laughing, or lifting. If you have a chronic cough that leads to bladder leakage, you may have cSUI.
“CSUI can be embarrassing, especially when you’re on the go. Not every cough will result in leakage, so it’s important to take control of this condition before it takes control of you,” said Newport News Clinical Research Director, Linda Schneider, MD, MBA, FAAFP.
Participants must meet the following criteria:
  • Must be a woman
  • Must be at least 18 years of age
  • Must have a persistent (chronic) cough
  • Must leak urine when you cough
If you complete the study, your participation will last approximately 22 weeks and include about 6 scheduled visits to the study clinic and 2 phone calls with the study team. You can stop taking part in this study at any time. If you choose not to take part or you choose to withdraw, medical care you receive outside the study will not be affected. The study doctor will discuss other treatment options with you.
To learn more about the MK-7264-042 study or to see if you may qualify to participate, please call (757) 232-8836 or visit
*There may be reasons why you cannot participate in the study. The study doctor will discuss this information with you. Thank you for your consideration.


Founded in 1992, Tidewater Physicians Multispecialty Group (TPMG) includes more than 220 primary care, specialty physicians and advanced practice clinicians in more than 85 locations throughout southeastern Virginia. TPMG’s mission is to provide superior healthcare that is responsible, physician-directed, and dedicated to keeping patients best interest foremost. The TPMG medical team includes expert physicians, nurse practitioners, physician assistants, nurses, medical assistants, diagnostic staff, and non-clinical staff all working together to provide consistent, compassionate, high-quality medical care. Learn more at

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