Colonial Endocrinology


New Town Photo


  • Tidewater Medical Center at New Town
  • 5424 Discovery Park Boulevard
  • Bldg. B, Suite 203
  • Williamsburg, VA 23188
  • Map



  • (757) 903-4808


Office Manager:

  • Jaynie Leffingwell

Office Hours:

  • Monday through Thursday, 8:00am to 5:00pm
  • Friday, 8:30am to 4:30pm

Accepting New Patients ~ Please call for additional information


Dr. Karen L. Knudsen is board certified in Endocrinology and Internal Medicine, as well as Endocrine Certification in Neck Ultrasound by the American Association of Clinical Endocrinologists.  She has a special interest in adrenal and pituitary disorders, women’s health, and thyroid and diabetes conditions.  Dr. Knudsen also performs thyroid ultrasounds and biopsies in the office.


Patients are seen by appointment.  Please contact our office to schedule an appointment.

New and Follow-up Appointments:

Please bring your insurance card(s), photo ID, a complete list of medications, and specialist co-pay (if it applies) to your visit.  All co-payments are due at the time of service.


If your insurance requires a specialist referral, please contact your primary care physician at least 3 days prior to your scheduled appointment.

Prescription Refills:

Prescription refill requests must be addressed at the time of your appointment, and any requests outside of this time will be addressed within 24 business hours.


If you have any questions or concerns about your bill, please call our Office Manager.